Article
The genetics of hypertension modifies the renal cell replication response induced by experimental diabetes.
Diabetes - 1 May 2002
Silveira Lilia A, Bacchi Carlos E, Pinto Glauce A, De Faria José B Lopes
Abstract excerpt
To investigate whether the genetics of hypertension modifies renal cell responses in experimental diabetes, we studied the renal cell replication and its regulation by two cyclin-dependent kinase (Cdk) inhibitors, p27(Kip1) and p21(Cip1), in prehypertensive spontaneously hypertensive rats (SHR) and their genetically normotensive counterparts, Wistar Kyoto (WKY) rats, with and without streptozotocin-induced...
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