Article
Genetic analysis of Brugada syndrome in Israel: two novel mutations and possible genetic heterogeneity.
Genetic testing - 1 Jan 2001
Levy-Nissenbaum E, Eldar M, Wang Q, Lahat H, Belhassen B, Ries L, Friedman E, Pras E
Abstract excerpt
Idiopathic ventricular fibrillation in patients with an electrocardiogram (ECG) pattern of right bundle branch block and ST-segment elevation in leads V1 to V3 (now frequently called Brugada syndrome) is associated with a high incidence of syncopal episodes or sudden death. The disease is inherited as an autosomal dominant trait. Mutations in SCN5A, a cardiac sodium channel gene, have been recently associated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.