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Article

Truncated hemoglobin HbN protects Mycobacterium bovis from nitric oxide.

Proceedings of the National Academy of Sciences of the United States of America - 30 Apr 2002

Ouellet Hugues, Ouellet Yannick, Richard Christian, Labarre Marie, Wittenberg Beatrice, Wittenberg Jonathan, Guertin Michel

Abstract excerpt

Mycobacterium tuberculosis, the causative agent of human tuberculosis, and Mycobacterium bovis each express two genes, glbN and glbO, encoding distantly related truncated hemoglobins (trHbs), trHbN and trHbO, respectively. Here we report that disruption of M. bovis bacillus Calmette-Guérin glbN caused a dramatic reduction in the NO-consuming activity of stationary phase cells, and that activity could be restored...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11959913
DOI: 10.1073/pnas.092017799
PMCID: PMC122874

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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