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Article

Up-regulation of interleukin-12 receptor expression in peripheral blood mononuclear cells of patients with HTLV-I-associated myelopathy/tropical spastic paraparesis.

Journal of the neurological sciences - 15 Apr 2002

Fujimoto Takeshi, Nakamura Tatsufumi, Nishiura Yoshihiro, Ichinose Katsuhiro, Furuya Takafumi, Shirabe Susumu, Eguchi Katsumi

Abstract excerpt

We previously reported elevated levels of serum interleukin-12 (IL-12) in association with increased interferon-gamma (IFN-gamma) levels in patients with human T-lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The interaction between IL-12 and IL-12 receptor (IL-12R) plays an important role in differentiation of the T helper type 1 (Th1) phenotype. In this study,...

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Identifiers

PMID: 11959151
DOI: 10.1016/s0022-510x(02)00016-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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