Article
Quinapril prevents restenosis after coronary stenting in patients with angiotensin-converting enzyme D allele.
Circulation journal : official journal of the Japanese Circulation Society - 1 Apr 2002
Okumura Kenji, Sone Takahito, Kondo Junichiro, Tsuboi Hideyuki, Mukawa Hiroaki, Tsuzuki Michitaka, Imai Hajime, Kamiya Hiroki, Mabuchi Yukio, Matsui Hideo, Hayakawa Tetsuo
Abstract excerpt
Restenosis after coronary artery stent implantation is attributed chiefly to intimal hyperplasia, which is prevented experimentally by angiotensin-converting enzyme (ACE) inhibitors. Therefore, the present study investigated whether the effect of quinapril, a tissue-specific ACE inhibitor, on the prevention of coronary restenosis differs according to ACE polymorphism. One hundred consecutive patients with...
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