Article
Preliminary evaluation of the cytotoxic and genotoxic potential of D-003: Mixture of very long chain fatty acids.
Teratogenesis, carcinogenesis, and mutagenesis - 1 Jan 2002
Gámez Rafael, Rodeiro Idania, Fernández Ivonne, Acosta Pilar Caridad
Abstract excerpt
D-003 is a mixture of very long chain aliphatic acids purified from sugar cane wax, wherein octacosanoic acid represents the major component. Previous experimental studies have shown that D-003 inhibits platelet aggregation in rodents. Also, its lowers total (TC) and low-density lipoprotein cholesterol (LDL-C) in normocholesterolemic rabbits in a dose-dependent manner and inhibits cholesterol biosynthesis in...
Topics
- 3T3 Cells
- Animals
- Dose-Response Relationship, Drug
- Fatty Acids
- Indicators and Reagents
- Mice
- Mutagenicity Tests
- Mutation
- Neutral Red
- Platelet Aggregation Inhibitors
- Salmonella typhimurium