Article
Resolution of lung inflammation by CD44.
Science (New York, N.Y.) - 5 Apr 2002
Teder Priit, Vandivier R William, Jiang Dianhua, Liang Jiurong, Cohn Lauren, Puré Ellen, Henson Peter M, Noble Paul W
Abstract excerpt
Successful repair after tissue injury and inflammation requires resolution of the inflammatory response and removal of extracellular matrix breakdown products. We have examined whether the cell-surface adhesion molecule and hyaluronan receptor CD44 plays a role in resolving lung inflammation. CD44-deficient mice succumb to unremitting inflammation following noninfectious lung injury, characterized by impaired...
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