Article
Intracellular cyclic AMP concentration is decreased in Salmonella typhimurium fur mutants.
Microbiology (Reading, England) - 1 Apr 2002
Campoy Susana, Jara Mónica, Busquets Núria, de Rozas Ana M Pérez, Badiola Ignacio, Barbé Jordi
Abstract excerpt
It is known that the Fur protein negatively regulates iron-uptake systems in different bacterial species, including Salmonella typhimurium. In this study it has been shown that the intracellular concentration of cyclic AMP (cAMP) is lower in a knockout S. typhimurium fur mutant than in the wild-type strain. According to this, the expression of two cAMP-regulated genes, such as pepE (encoding an alpha-aspartyl...
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