Article
The distribution of DQ genes in the Saharawi population provides only a partial explanation for the high celiac disease prevalence
1 Dec 2001
Abstract excerpt
Celiac disease (CD) is a multifactorial disorder of the small intestine caused by a permanent dietary intolerance to gluten. The combined presence of the HLA class II DQA1*0501 and DQB1*0201 alleles represents the major genetic component for disease predisposition. It has been shown that the Saharawi refugees living in northern Africa have a very high frequency of CD. In the present study we analysed this...
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