Article
Simple multiplex genotyping by surface-enhanced resonance Raman scattering.
Analytical chemistry - 1 Mar 2002
Graham Duncan, Mallinder Benjamin J, Whitcombe David, Watson Nigel D, Smith W Ewen
Abstract excerpt
The accurate detection of DNA sequences is essential for a variety of post human genome projects including detection of specific gene variants for medical diagnostics and pharmacogenomics. A specific DNA sequence detection assay based on surface-enhanced resonance Raman scattering (SERRS) and an amplification refractory mutation system (ARMS) is reported. Initially, generation of PCR products was achieved by...
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