Article
The norepinephrine transporter gene and attention-deficit hyperactivity disorder.
American journal of medical genetics - 8 Apr 2002
Barr Cathy L, Kroft Jamie, Feng Yu, Wigg Karen, Roberts Wendy, Malone Molly, Ickowicz Abel, Schachar Russell, Tannock Rosemary, Kennedy James L
Abstract excerpt
The adrenergic system plays a known role in attentional systems and a suspected causal role in attention-deficit hyperactivity disorder (ADHD), based on evidence from pharmacological interventions and animal models. The efficacy of the highly selective noradrenergic reuptake inhibitor, tomoxetine, in treating ADHD symptoms supports the system's role in ADHD and points to the norephinephrine transporter as a...
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