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Article

Activation of caspase-9 is required for UV-induced apoptosis of human keratinocytes.

The Journal of biological chemistry - 31 May 2002

Sitailo Leonid A, Tibudan Shalini S, Denning Mitchell F

Abstract excerpt

UV radiation from the sun activates both the membrane death receptor and the intrinsic or mitochondrial apoptotic signaling pathways in epidermal keratinocytes, triggering apoptosis and affording protection against skin cancer formation. We have investigated the involvement of caspase-9 in the UV...

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Identifiers

PMID: 11919192
DOI: 10.1074/jbc.M200401200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11919192-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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