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Article

Co-selection of the H63D mutation and the HLA-A29 allele: a new paradigm of linkage disequilibrium?

Immunogenetics - 1 Mar 2002

Cardoso Carla S, Alves Helena, Mascarenhas Mónica, Gonçalves Ricardo, Oliveira Pedro, Rodrigues Pedro, Cruz Eugénia, de Sousa Maria, Porto Graça

Abstract excerpt

The major histocompatibility complex (MHC) shows a remarkable conservation of particular HLA antigens and haplotypes in linkage disequilibrium in most human populations, suggesting the existence of a convergent evolution. A recent example of such conservation is the association of particular HLA haplotypes with the HFE mutations. With the objective of exploring the significance of that association, the present...

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Source

Identifiers

PMID: 11904676
DOI: 10.1007/s00251-001-0414-8

Genes

HFE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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