Article
Prevalence of circulating <i>Treponema pallidum</i> DNA and RNA in blood donors with confirmed‐positive syphilis tests
1 Jan 2002
Abstract excerpt
BACKGROUND: Although there have been no well-documented cases of transfusion-transmitted syphilis in more than 30 years, serologic tests for syphilis (STS) continues to be required for donated blood. Previously, the methods for detecting viable spirochetes were dependent on the use of the rabbit infectivity test. DNA PCR and RNA RT-PCR were applied to assess the presence of Treponema pallidum DNA or RNA in blood...
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