Molecular Characterization of Syphilis in Patients in Canada: Azithromycin Resistance and Detection of<i>Treponema pallidum</i>DNA in Whole-Blood Samples versus Ulcerative Swabs

Abstract excerpt

Although detection of Treponema pallidum DNA in whole-blood specimens of syphilis patients has been reported, it is uncertain at what stage of the disease such specimens are most suitable for the molecular diagnosis of syphilis. Also, few studies have directly compared the different gene targets for routine laboratory diagnostic usage in PCR assays. We examined 87 specimens from 68 patients attending two urban...

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