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Article

Impaired stratum corneum hydration in mice lacking epidermal water channel aquaporin-3.

The Journal of biological chemistry - 10 May 2002

Ma Tonghui, Hara Mariko, Sougrat Rachid, Verbavatz Jean-Marc, Verkman A S

Abstract excerpt

The water and solute transporting properties of the epidermis have been proposed to be important determinants of skin moisture content and barrier properties. The water/small solute-transporting protein aquaporin-3 (AQP3) was found by immunofluorescence and immunogold electron microscopy to be expressed at the plasma membrane of epidermal keratinocytes in mouse skin. We studied the role of AQP3 in stratum corneum...

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Source

Identifiers

PMID: 11880378
DOI: 10.1074/jbc.M200925200

Genes

AQP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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