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Article

Neuronal intranuclear inclusions in SCA2: a genetic, morphological and immunohistochemical study of two cases.

Brain : a journal of neurology - 1 Mar 2002

Pang Joanna T, Giunti Paola, Chamberlain Susan, An Shu F, Vitaliani Roberta, Scaravilli Tomaso, Martinian Lillian, Wood Nicholas W, Scaravilli Francesco, Ansorge Olaf

Abstract excerpt

Spinocerebellar ataxia 2 (SCA2) belongs to the family of autosomal dominant cerebellar ataxias (ADCA), a genetically heterogeneous group of neurodegenerative diseases. The SCA2 gene maps to chromosome 12q24 and the causative mutation involves the expansion of a CAG repeat within the coding region of the gene. Pathologically, SCA2 presents as olivo-ponto-cerebellar atrophy (OPCA). We present the cases of a...

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PMID: 11872620
DOI: 10.1093/brain/awf060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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