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Article

Clinicopathologic investigation of a family with expanded SCA8 CTA/CTG repeats.

Neurology - 24 Oct 2006

Ito H, Kawakami H, Wate R, Matsumoto S, Imai T, Hirano A, Kusaka H

Abstract excerpt

We investigated a family manifesting progressive ataxia, with expanded SCA8 CTA/CTG repeats. Neuropathologically, degeneration of Purkinje, inferior olivary, and nigral neurons and periaqueductal gliosis were evident. The sites of Purkinje cell loss were occupied by fibrillary accumulations. The remaining Purkinje cells showed somatic sprouts, and intracytoplasmic 1C2-positive granular structures were...

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Identifiers

PMID: 17060579
DOI: 10.1212/01.wnl.0000240256.13633.7b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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