Differential T and B Cell Responses againstMycobacterium tuberculosisHeparin‐Binding Hemagglutinin Adhesin in Infected Healthy Individuals and Patients with Tuberculosis

Abstract excerpt

Because only 10% of individuals infected with Mycobacterium tuberculosis will eventually develop disease, antigens that are recognized differently by the immune systems of infected healthy and diseased subjects may constitute potential vaccine candidates. Here, the heparin-binding hemagglutinin adhesin (HBHA) is identified as such an antigen. Lymphocytes from 60% of healthy infected individuals (n=25) produced...

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