Article
Coupling of enhancer and insulator properties identified in two retrotransposons modulates their mutagenic impact on nearby genes.
Molecular and cellular biology - 1 Mar 2002
Conte Caroline, Dastugue Bernard, Vaury Chantal
Abstract excerpt
We recently reported a novel transposition system in which two retroelements from Drosophila melanogaster, ZAM and Idefix, are highly mobilized and preferentially insert within intergenic regions. Among the loci where new copies are detected, a hot spot for their insertion was identified at the white locus, where up to three elements occurred within a 3-kb fragment upstream of the transcriptional start site of...
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