Article
[Study on the association of pathologic myopia with HLA-DQB1 gene].
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology - 1 Jul 2001
Li S, Ji B, Chu R, Chen T, Luo Y, Lu Y, Zhu D, Geng Z
Abstract excerpt
OBJECTIVE: To investigate the association of pathologic myopia (PM) with HLA-DQB1 alleles in order to study the pathogenesis of PM. METHODS: The genome DNA of 66 patients with PM was extracted from the blood. The second exon of the HLA-DQB1 gene was amplified by polymerase chain reaction (PCR), and individual PCR products were digested by allele specific restriction enzymes of Hae III, BssH II, Apa I, BsaH I, Hae...
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