Physiology of iron transport and the hemochromatosis gene.

Abstract excerpt

Iron is essential for fundamental cell functions but is also a catalyst for chemical reactions involving free radical formation, potentially leading to oxidative stress and cell damage. Cellular iron levels are therefore carefully regulated to maintain an adequate substrate while also minimizing the pool of potentially toxic "free iron." The main control of body iron homeostasis in higher organisms is placed in...

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• Transferrin
• Hemochromatosis
• Hemochromatosis Protein
• Hemoglobins
• Intestinal Absorption