Article
Approaches to understanding susceptibility to nephropathy: from genetics to genomics.
Kidney international - 1 Jan 2002
Iyengar Sudha K, Schelling Jeffrey R, Sedor John R
Abstract excerpt
The incidence of end-stage renal disease (ESRD) is increasing worldwide despite efforts to slow the progression of chronic renal failure (CRF) by controlling blood pressure and hyperglycemia. Two available therapies for ESRD, dialysis and transplantation, are expensive and are at best palliative. Recently, data from several laboratories have demonstrated that ESRD is under substantial genetic control, and efforts...
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