Article
Persistence of tumor DNA in plasma of breast cancer patients after mastectomy.
Annals of surgical oncology - 1 Jan 2000
Silva Jose M, Garcia Jose M, Dominguez Gemma, Silva Javier, Miralles Celia, Cantos Blanca, Coca Santiago, Provencio Mariano, España Pilar, Bonilla Felix
Abstract excerpt
BACKGROUND: We investigated tumor DNA changes before and after mastectomy in the plasma of breast cancer patients with no disseminated disease and eventually investigated these changes' relationship to specific pathological parameters of the tumors. METHODS: We studied 41 patients. DNA extracted from tumor and normal breast tissues, mononuclear blood cells, and plasma was used for molecular studies. Alterations...
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