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Article

Wide clinical variability in a family with a CACNA1A T666m mutation: hemiplegic migraine, coma, and progressive ataxia.

Pediatric neurology - 1 Jan 2002

Wada Takahito, Kobayashi Norio, Takahashi Yoshio, Aoki Tomoko, Watanabe Takako, Saitoh Shinji

Abstract excerpt

We report a Japanese family carrying a T666M missense mutation of CACNA1A. Affected members demonstrated a strikingly wide clinical spectrum including migraine, hemiplegia, coma, and progressive cerebellar ataxia. Despite such variability of the clinical features, they demonstrated similar magnet...

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Identifiers

PMID: 11814735
DOI: 10.1016/s0887-8994(01)00371-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11814735-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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