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Article

CACNA1A-Related Channelopathies: Clinical Manifestations and Treatment Options.

Handbook of experimental pharmacology - 1 Jan 2023

Indelicato Elisabetta, Boesch Sylvia

Abstract excerpt

In the last decade, variants in the Ca2+ channel gene CACNA1A emerged as a frequent aetiology of rare neurological phenotypes sharing a common denominator of variable paroxysmal manifestations and chronic cerebellar dysfunction. The spectrum of paroxysmal manifestations encompasses migraine with hemiplegic aura, episodic ataxia, epilepsy and paroxysmal non-epileptic movement disorders. Additional chronic...

Topics

Humans
Ataxia
Calcium Channels
Cerebellar Ataxia
Channelopathies
Migraine Disorders
Mutation

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36592223
DOI: 10.1007/164_2022_625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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