Article
Loss of glutathione S-transferase (GST) mu phenotype in colorectal adenocarcinomas from patients with a GSTM1 positive genotype.
Cancer letters - 8 Mar 2002
Barker Heather J, Alpert Lesley C, Compton Carolyn C, Maslen Ann, Kirby Gordon M
Abstract excerpt
Glutathione S-transferase (GST) mu phenotype was assessed in colon tissue from patients with ulcerative colitis and colorectal neoplasms that were positive for GSTM1 genotype. GST mu protein (enzyme linked immunosorbent assay) was absent in 2/9 unaffected colon tissue (22.3%), 4/13 tissues with chronic ulcerative colitis (CUC) (30.7%), 4/11 adenomas (36.4%) and 7/14 adenocarcinomas (50.0%; P<or=0.05)....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.