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Article

Genotyping in the MHC locus: potential for defining predictive markers in sarcoidosis.

Respiratory research - 1 Jan 2002

Seitzer Ulrike, Gerdes Johannes, Müller-Quernheim Joachim

Abstract excerpt

In sarcoidosis, host genetic factors are discussed as contributing to disease susceptibility and course. Since tumor necrosis factor (TNF)-alpha is a central mediator of granuloma formation and since elevated TNF-alpha levels are found during active phases of sarcoidosis, genetic polymorphisms correlating with influences on TNF-alpha levels are of special interest. The complete sequencing of the MHC region and...

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Share to TNF gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Major Histocompatibility Complex

Share to Polymorphism, Genetic

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Share to Quantitative Trait Loci

Share to Sarcoidosis, Pulmonary

Source

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Identifiers

PMID: 11806841
DOI: 10.1186/rr178
PMCID: PMC64817

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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