Article
Investigation of the CACNA1A gene as a candidate for typical migraine susceptibility.
American journal of medical genetics - 8 Dec 2001
Lea R A, Curtain R P, Hutchins C, Brimage P J, Griffiths L R
Abstract excerpt
Typical migraine is a complex neurological disorder comprised of two main subtypes: migraine with (MA) and without aura (MO). The disease etiology is still unclear, but family studies provide strong evidence that defective genes play an important role. Familial hemiplegic migraine (FHM) is a very rare and severe subtype of MA. It has been proposed that FHM and MA may have a similar genetic etiology. Therefore,...
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