Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Linkage and mutation analysis in two Taiwanese families with long QT syndrome.

Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Nov 2001

Ko Y L, Tai D Y, Chen S A, Lee-Chen G J, Chu C H, Lin M W

Abstract excerpt

Long QT syndrome (LQT) is a cardiovascular disorder causing syncope and sudden death from arrhythmias. Mutations in KCNQ1, KCNH2, KCNE1, KCNE2, and SCN5A genes encoding cardiac potassium and sodium ion channels cause LQT. Two Taiwanese LQT families were screened for mutations in these ion channel genes. In family H87, the diagnosis was made in the 25-year-old female proband and six family members based on...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Codon, Nonsense
Share to Genetic Linkage
Share to Long QT Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation, Missense

Share to Pedigree

Share to Polymorphism, Single-Stranded Conformational

Share to Potassium Channels

Share to Sodium Channels

Source

Identifiers

PMID: 11802537

Genes

KCNH2
KCNQ1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Linkage and mutation analysis in two Taiwanese families with long QT syndrome.PMID 11802537Read ↗

Mutation analysis of potassium channel genes KCNQ1 and KCNH2 in patients with long QT syndrome.Semantic proximity Read ↗

Genotype-based clinical manifestation and treatment of Chinese long QT syndrome patients with KCNQ1 mutations - R380S and W305L.Semantic proximity Read ↗

Identification of a new SCN5A mutation, D1840G, associated with the long QT syndrome. Mutations in brief no. 153. Online.Semantic proximity Read ↗

A missense mutation (G604S) in the S5/pore region of HERG causes long QT syndrome in a Chinese family with a high incidence of sudden unexpected death.Semantic proximity Read ↗

KCNQ1 and KCNH2 mutations associated with long QT syndrome in a Chinese population.Semantic proximity Read ↗

Identification of a Kir3.4 mutation in congenital long QT syndrome.Semantic proximity Read ↗

A candidate locus approach identifies a long QT syndrome gene mutation.Semantic proximity Read ↗

Mutation Analysis of KCNQ1, KCNH2 and SCN5A Genes in Taiwanese Long QT Syndrome Patients.Semantic proximity Read ↗

Novel missense mutation in the cyclic nucleotide-binding domain of HERG causes long QT syndrome.Semantic proximity Read ↗

Single nucleotide deletion mutation of KCNH2 gene is responsible for LQT syndrome in a 3-generation Korean family.Semantic proximity Read ↗

[Novel mutations of potassium channel KCNQ1 S145L and KCNH2 Y475C genes in Chinese pedigrees of long QT syndrome].Semantic proximity Read ↗

Genetic homozygosity in a diverse population: An experience of long QT syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.