Article
In the absence of the first membrane-spanning segment of subunit 4(b), the yeast ATP synthase is functional but does not dimerize or oligomerize.
The Journal of biological chemistry - 22 Mar 2002
Soubannier Vincent, Vaillier Jacques, Paumard Patrick, Coulary Benedicte, Schaeffer Jacques, Velours Jean
Abstract excerpt
The N-terminal portion of the mitochondrial b-subunit is anchored in the inner mitochondrial membrane by two hydrophobic segments. We investigated the role of the first membrane-spanning segment, which is absent in prokaryotic and chloroplastic enzymes. In the absence of the first membrane-spanning segment of the yeast subunit (subunit 4), a strong decrease in the amount of subunit g was found. The mutant ATP...
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