Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Non-conventional trafficking of the cystic fibrosis transmembrane conductance regulator through the early secretory pathway.

The Journal of biological chemistry - 29 Mar 2002

Yoo Jin-San, Moyer Bryan D, Bannykh Sergei, Yoo Hyeon-Mi, Riordan John R, Balch William E

Abstract excerpt

The mechanism(s) of cystic fibrosis transmembrane conductance regulator (CFTR) trafficking from the endoplasmic reticulum (ER) through the Golgi apparatus, the step impaired in individuals afflicted with the prevalent CFTR-DeltaF508 mutation leading to cystic fibrosis, is largely unknown. Recent morphological observations suggested that CFTR is largely absent from the Golgi in situ (Bannykh, S. I., Bannykh, G....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ADP-Ribosylation Factor 1
Share to Cystic Fibrosis Transmembrane Conductance Regulator

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Endoplasmic Reticulum

Share to Glycosylation

Share to Luminescent Proteins

Share to Monomeric GTP-Binding Proteins

Share to Qa-SNARE Proteins

Share to Vesicular Transport Proteins

Source

Identifiers

PMID: 11799116
DOI: 10.1074/jbc.M110263200

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Non-conventional trafficking of the cystic fibrosis transmembrane conductance regulator through the early secretory pathway.PMID 11799116Read ↗

Control of cystic fibrosis transmembrane conductance regulator membrane trafficking: not just from the endoplasmic reticulum to the Golgi.Semantic proximity Read ↗

Traffic pattern of cystic fibrosis transmembrane regulator through the early exocytic pathway.Semantic proximity Read ↗

COPII-dependent export of cystic fibrosis transmembrane conductance regulator from the ER uses a di-acidic exit code.Semantic proximity Read ↗

Sec16A is critical for both conventional and unconventional secretion of CFTR.Semantic proximity Read ↗

The role of regulated CFTR trafficking in epithelial secretionSemantic proximity Read ↗

Endocytic trafficking of CFTR in health and diseaseSemantic proximity Read ↗

Endocytic Trafficking Routes of Wild Type and ΔF508 Cystic Fibrosis Transmembrane Conductance RegulatorSemantic proximity Read ↗

Traffic COPs of the Early Secretory PathwaySemantic proximity Read ↗

N-glycans are direct determinants of CFTR folding and stability in secretory and endocytic membrane traffic.Semantic proximity Read ↗

Identification of molecular determinants that modulate trafficking of DeltaF508 CFTR, the mutant ABC transporter associated with cystic fibrosis.Semantic proximity Read ↗

C-terminal Truncations Destabilize the Cystic Fibrosis Transmembrane Conductance Regulator without Impairing Its BiogenesisSemantic proximity Read ↗

Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic ReticulumSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.