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Article

Involvement of ATM missense variants and mutations in a series of unselected breast cancer cases.

Genes, chromosomes & cancer - 1 Feb 2002

Rodriguez Carmen, Vallès Hélène, Causse Annick, Johannsdottir Vala, Eliaou Jean-François, Theillet Charles

Abstract excerpt

It has been proposed that women carrying heterozygous mutations of the ATM gene could be at increased risk of developing breast cancer. However, data in the literature are contrasting and no firm conclusion has been reached. Our aim was to verify whether ATM inactivation could play a role in breast tumor development. Following the classical tumor suppressor inactivation scheme, tumors showing loss of...

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Source

Identifiers

PMID: 11793440
DOI: 10.1002/gcc.1222

Genes

ATM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Involvement of ATM missense variants and mutations in a series of unselected breast cancer cases.PMID 11793440Read ↗

Rare variants in the ATM gene and risk of breast cancer.Semantic proximity Read ↗

Missense mutations but not allelic variants alter the function of ATM by dominant interference in patients with breast cancer.Semantic proximity Read ↗

Loss of heterozygosity at 11q23.1 in breast carcinomas: indication for involvement of a gene distal and close to ATM.Semantic proximity Read ↗

Identification of germline missense mutations and rare allelic variants in the ATM gene in early-onset breast cancer.Semantic proximity Read ↗

Missense variants in ATM in 26,101 breast cancer cases and 29,842 controls.Semantic proximity Read ↗

Somatic ATM mutations indicate a pathogenic role of ATM in B-cell chronic lymphocytic leukemia.Semantic proximity Read ↗

High incidence of cancer in a family segregating a mutation of the ATM gene: possible role of ATM heterozygosity in cancer.Semantic proximity Read ↗

Somatic ATM Mutations Indicate a Pathogenic Role of ATM in B-Cell Chronic Lymphocytic LeukemiaSemantic proximity Read ↗

The ATM gene and breast cancer: is it really a risk factor?Semantic proximity Read ↗

Spectrum of ATM gene mutations in a hospital-based series of unselected breast cancer patients.Semantic proximity Read ↗

Contribution of mutations in ATM to breast cancer development in the Czech population.Semantic proximity Read ↗

ATM mutations in cancer families.Semantic proximity Read ↗

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