Article
Cytokine gene polymorphism in recurrent acute otitis media.
Archives of otolaryngology--head & neck surgery - 1 Jan 2002
Joki-Erkkilä Veli-Pekka, Puhakka Heikki, Hurme Mikko
Abstract excerpt
BACKGROUND: There is increasing evidence that a strong genetic component is involved in the predisposition to recurrent acute otitis media (rAOM). Cytokines play a key role in the pathogenesis of otitis media. Constitutional polymorphisms in cytokine genes may lead to individual variations in cytokine secretion. OBJECTIVE: To elucidate the role of cytokine gene polymorphisms in rAOM. SETTING: University hospital....
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