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Article

BCLW mediates survival of postmitotic Sertoli cells by regulating BAX activity.

Developmental biology - 15 Nov 2001

Ross A J, Amy S P, Mahar P L, Lindsten T, Knudson C M, Thompson C B, Korsmeyer S J, MacGregor G R

Abstract excerpt

Male mice deficient in BCLW, a death-protecting member of the BCL2 family, are sterile due to an arrest in spermatogenesis that is associated with a gradual loss of germ cells and Sertoli cells from the testis. As Bclw is expressed in both Sertoli cells and diploid male germ cells, it has been unclear which of these cell types requires BCLW in a cell-autonomous manner for survival. To determine whether death of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11784036
DOI: 10.1006/dbio.2001.0445

Genes

BAX
BCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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