Article
Transplantation of cultured human neural progenitor cells into rat brain: migration and differentiation.
Bulletin of experimental biology and medicine - 1 Oct 2001
Aleksandrova M A, Poltavtseva R A, Marei M V, Revishchin A V, Saburina I N, Dubrovina I V, Korochkin L I, Sukhikh G T
Abstract excerpt
We studied the fate in vitro cultured human stem/progenitor cells after transplantation into rat brain. The cells from human fetuses at 8-12 weeks' gestation were cultured in vitro for 14 days and transplanted into the brain of 10-day-old and adult rats. Microscopic examination showed that human stem/progenitor cells migrated into various regions of rat brain. Immunohistochemical assay demonstrated that some...
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