Article
A comparison of proliferative capacity and passaging potential between neural stem and progenitor cells in adherent and neurosphere cultures.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Nov 2011
Sun Tao, Wang Xiao-Jing, Xie Shan-Shan, Zhang Dao-Lai, Wang Xu-Ping, Li Bo-Qin, Ma Wu, Xin Hua
Abstract excerpt
Neural stem and progenitor cells (NSPCs) can be isolated from the fetal or adult brain and expanded in culture for potential use in basic research, drug discovery and cell therapy. In the present study, two culture systems have been commonly used to maintain and expand NSPCs isolated from mammalian CNS: neurosphere and adhesive substrate-bound monolayer culture. NSPCs were isolated from the neuroepithelium of E14...
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