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Article

Molecular modelling of disease-causing single-nucleotide polymorphisms in collagen.

SAR and QSAR in environmental research - 1 Jan 2001

Milchevsky J V, Ramensky V E, Esipova N G, Tumanyan V G, Zorov B S

Abstract excerpt

The purpose of the work was to investigate at the molecular structural and energy levels the consequence of amino acid substitutions in collagen that cause systemic diseases. The data have been systematized on defects in human collagen III, and the patterns of single-nucleotide polymorphisms collected. Then molecular mechanics calculations were performed for native and mutant collagen molecule fragments. The...

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Share to Amino Acid Substitution
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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PMID: 11769121
DOI: 10.1080/10629360108033246

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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