Article
Does the shared epitope genotype influence either the susceptibility to or the phenotype of corneal melting?
Eye (London, England) - 1 Aug 2001
McKibbin M, Clark B, Isaacs J D, Morrell A J, Griffiths B, Morgan A W, Gooi H C
Abstract excerpt
PURPOSE: To investigate the role of the shared epitope alleles in determining susceptibility to and the phenotype of corneal melting in patients with rheumatoid arthritis (RA). METHODS: The HLA class 1 and 2 genotype was determined for 17 patients with rheumatoid-associated comeal melting by the phototyping method. HLA-DR4 subtyping was performed by PCR sequence-based typing. The frequency of all the shared...
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