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Article

Mutations in the factor IX gene (F9) during the past 150 years have relative rates similar to ancient mutations.

Human mutation - 1 Jan 2002

Feng Jinong, Drost Joni B, Scaringe William A, Liu Qiang, Sommer Steve S

Abstract excerpt

Pollutants and dietary mutagens have been associated with somatic mutation and cancer, but the extent of their influence on germline mutation is not clear. Since deleterious germline mutations can be transmitted for thousands of years, any influence on germline mutation from the vast increase in man-made chemicals of the past 150 years would be an important public health issue. Observed disease causing mutations...

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PMID: 11754103
DOI: 10.1002/humu.10018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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