Article
An analysis of published trials of interferon monotherapy in children with chronic hepatitis C.
Journal of pediatric gastroenterology and nutrition - 1 Jan 2002
Jacobson Karen R, Murray Karen, Zellos Aglaia, Schwarz Kathleen B
Abstract excerpt
BACKGROUND: Although no therapeutic regimen has received Food and Drug Administration approval for treating children with chronic hepatitis C viral infection (CHC), there have been a number of pediatric interferon-alpha (IFN-alpha) trials. The purpose of this study was to perform a critical review of these trials to determine 1) end-of-treatment (ETR) and sustained-response (SR) rates, 2) predictors of response...
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