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Article

Characterization of the yaeL gene product and its S2P-protease motifs in Escherichia coli.

Gene - 27 Dec 2001

Kanehara K, Akiyama Y, Ito K

Abstract excerpt

An Escherichia coli open reading frame, yaeL, encodes a predicted homolog of human site-2 protease (S2P), a putative membrane-bound zinc metalloproteinase involved in the proteolytic activation of regulatory factors for sterol biosynthesis and for stress responses. The potential importance of YaeL in processes analogous to the regulated intramembrane proteolysis in E. coli prompted us to characterize it. Cell...

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Identifiers

PMID: 11750129
DOI: 10.1016/s0378-1119(01)00823-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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