[Hodgkin's disease: biology can help the physician towards new prognostic factors and new therapeutic approaches].

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Article

[Hodgkin's disease: biology can help the physician towards new prognostic factors and new therapeutic approaches].

Bulletin du cancer - 1 Nov 2001

Rubio M T, Ghesquières H, Blay J Y, Salles G

Abstract excerpt

Hodgkin's disease is a lymphoma pathology characterized, histology wise, by the presence of rare tumoral cells, known as Reed-Sternberg cells, in a polymorph, inflammatory and reactive cell environment. Recent studies in molecular biology have shown that the Reed-Sternberg cell is mainly derived from a post germinal B lymphoid cell. Reed-Sternberg cell is also known to express characteristic molecules of an...

Topics

Apoptosis
Cell Transformation, Neoplastic
Cytokines
Genotype
Herpesvirus 4, Human
Hodgkin Disease
Humans
Immune Tolerance
Immunity, Cellular
Infectious Mononucleosis
Killer Cells, Natural
Phenotype
Prognosis
Reed-Sternberg Cells
T-Lymphocytes

Source

Open in PubMed

Identifiers

PMID: 11741802

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