Article
Pharmacogenomics: the promise of personalized medicine.
AAPS pharmSci - 1 Jan 2000
Mancinelli L, Cronin M, Sadée W
Abstract excerpt
Pharmacogenetics and pharmacogenomics deal with the genetic basis underlying variable drug response in individual patients. The traditional pharmacogenetic approach relies on studying sequence variations in candidate genes suspected of affecting drug response. On the other hand, pharmacogenomic studies encompass the sum of all genes, i.e., the genome. Numerous genes may play a role in drug response and toxicity,...
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