Article
The effect of the Gly16Arg polymorphism of the beta(2)-adrenergic receptor gene on plasma free fatty acid levels is modulated by physical activity.
The Journal of clinical endocrinology and metabolism - 1 Dec 2001
Meirhaeghe A, Luan J, Selberg-Franks P, Hennings S, Mitchell J, Halsall D, O'Rahilly S, Wareham N J
Abstract excerpt
The lipolytic effects of catecholamines are mediated through members of the beta(2)-adrenergic receptor (BAR-2) family. Previous studies have suggested that genetic variants in the BAR-2 gene may be associated with obesity in some populations. To our knowledge, no studies have directly examined the effects of this polymorphism on circulating nonesterified fatty acid (NEFA) levels. To explore this issue further, a...
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