Article
Resistance and cross-resistance to abacavir.
HIV medicine - 1 Jul 2001
Moyle G
Abstract excerpt
BACKGROUND: Abacavir (ABC) is a potent nucleoside reverse transcriptase inhibitor (NRTI) used in multi-drug antiretroviral regimens and in combination with other NRTIs, protease and/or non-nucleoside reverse transcriptase inhibitors (NNRTIs) in both treatment naive and treatment experienced patients. PATTERNS OF RESISTANCE: Resistance to ABC has been demonstrated in vitro and in vivo. Patterns of emerging...
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