Article
Quantitative, phenotypic, and functional evaluation of basophils in myelodysplastic syndromes.
European journal of clinical investigation - 1 Oct 2001
Füreder W, Schernthaner G H, Ghannadan M, Hauswirth A, Sperr W R, Semper H, Majlesi Y, Zwirner J, Götze O, Bühring H J, Lechner K, Valent P
Abstract excerpt
BACKGROUND: The myelodysplastic syndromes (MDS) are a group of clonal haematological disorders characterized by cytopenia(s), reduced differentiation-capacity of myeloid cells, and impaired leukocyte function. However, little is known so far about basophil granulocytes in MDS. DESIGN: We have compared the numbers, phenotype and function of basophils in MDS patients with those in healthy subjects. A total numer of...
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