Article
Candidate gene case-control association studies: advantages and potential pitfalls.
British journal of clinical pharmacology - 1 Nov 2001
Daly A K, Day C P
Abstract excerpt
There is increasing information on the importance of genetic polymorphisms in human genes. Polymorphisms occur on average once every 500-1000 base pairs in the human genome and are useful in the identification of genes involved in human disease. Some genetic polymorphisms have functionally significant effects on the gene product and are the most useful type of polymorphism in disease association studies while...
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