Oxygen tension and nutrient starvation are major signals that regulate agfD promoter activity and expression of the multicellular morphotype in Salmonella typhimurium.

Abstract excerpt

Expression of multicellular behaviour (rdar morphotype) is a characteristic of wild-type Salmonella typhimurium strains. The key target for the regulation of rdar morphotype expression is the agfD promoter. The regulation of two rdar morphotypes, regulated and semi-constitutive (the latter differs from the former by the insertion of A after position -17), by various environmental conditions was studied using...

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