Article
Expression and function of CD43 and CDw60 on T cells from patients with atopic dermatitis.
Acta dermato-venereologica - 1 Jan 2000
Higashi N, Wu K, Grønhøj Larsen C, Deleuran M, Kawana S, Yamamoto K, Thestrup-Pedersen K
Abstract excerpt
Signalling via the CD43 and CDw60 epitopes has been reported as providing two novel pathways of T-lymphocyte activation. In Wiskott-Aldrich syndrome, which has atopic eczema-like skin symptoms, there is a defective expression of CD43, while CDw60 is strongly expressed on T cells from rheumatoid arthritis synovial fluid and from psoriatic skin lesions, and on blood mononuclear cells from patients with cutaneous...
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